Second-hand machinery for sale (45)

Condition: like new (used), Year of construction: 2021, operating hours: 100 h, functionality: fully functional, machine/vehicle number: 13902, Equipment: low noise, Groninger MFCS 201 RH – Filling, closing, and labeling machine – Year of manufacture: 2021 – Like new For sale is a high-quality, fully automatic filling, closing, and labeling machine from the German manufacturer Groninger GmbH & Co. KG. Type: MFCS 201 RH, machine no. 13902, year of manufacture 2021. The machine was installed and put into operation at our location in Solingen in 2022. The machine has been used very little and is in almost new condition. In total, only approximately 300,000 containers have been filled with it. For the majority of the time, the system was idle and not used in continuous or multi-shift operation. Individual components, in particular the integrated labeling system, were not used at all in our production facility. The verifiable new price of the machine without laminar flow was €630,000 net. The machine is sold without the laminar flow unit. The system is designed for a capacity of up to 60 units/min or approximately 3,600 units/hour. The existing format is designed for micro-screw caps. The documented filling volume is approximately 0.3 ml. The existing container has a diameter of approximately 11 mm and a height of approximately 43.9 mm; the screw cap has a diameter of approximately 13 mm. Other formats are possible; however, format parts would then need to be manufactured. The machine features a Groninger peristaltic/hose pump filling system with a filling needle and automatic filling needle movement. The containers are automatically fed via a vibrating hopper and sorting unit and transported through the machine via a timed conveyor. The screw caps are also sorted and fed fully automatically. The system features pre-closing and final closing stations, closure control, and automatic good/bad part sorting. Integrated is a fully automatic all-round labeling station with a servo-motorized CAB labeling system. In addition, a Markem thermal transfer printer is integrated for variable markings such as batch and date, as well as a check for "print present." The system also features recipe management, user management, diagnostics and service functions, a piece counter, alarm/event displays, and remote maintenance capabilities via a VPN router. An original Groninger EC/EU declaration of conformity is available. The machine complies with, among other things, Machinery Directive 2006/42/EC and the EMC Directive 2014/30/EU. Itjdpfsz R A Sgex Ap Den The complete, extensive Groninger original documentation is available, including operating, maintenance, and repair documents, spare parts and wear parts lists, format documents, pneumatic and layout plans, and FAT documentation. The machine has been professionally disassembled by us and is currently stored safely. The disassembly was documented in a video. We can support the buyer in reassembling the machine and explain the operation and functionality of the machine. Alternatively, Groninger can, of course, be brought in for assembly, commissioning, and service. There is also an existing order for this machine that the new buyer can fulfill if the client wishes. The client is from Switzerland and has an order volume of €60,000 per year. Location: 42699 Solingen, Germany. Inspection possible by appointment. We will gladly provide further technical documents upon request from a seriously interested buyer.

Condition: new, Year of construction: 2020, functionality: fully functional, BOSCH Pharmatec CIP System 8X0400 – Never Used – GMP Pharma Version For sale is a complete BOSCH Pharmatec CIP (Cleaning in Place) system in new condition (Never Used). The system was manufactured in 2019/2020 but was never put into operation. Since delivery, it has been stored professionally and is in excellent condition. The system was developed according to the highest GMP standards and is ideally suited for the pharmaceutical, biotechnology, vaccine, and food industries. Technical Data Manufacturer: Bosch Pharmatec GmbH (now Syntegon) Type: CIP Unit 8X0400 Year of Construction: 2019 / 2020 Condition: Never Used / New GMP Version Stainless Steel Design CE Marking Immediately available Scope of Supply Itodpjzpy Nzjfx Ap Don BOSCH Pharmatec CIP Unit 8X0400 Stainless Steel Water Tanks CIP Satellites Complete Pump Skids KPA Hygienic Pumps Endress+Hauser Measuring and Control Technology Hygienic Stainless Steel Piping Valves and Fittings Heat Exchangers Original Bosch Documentation P&ID Flow Diagrams Layout Drawings and Technical Documents Important Note The system is offered without pneumatic components and without control (automation). This allows the system to be individually adapted to the buyer's requirements and equipped with a modern PLC, pneumatic, and automation solution as desired. This offers maximum flexibility for new installations or integration into existing production facilities. Application Areas Pharmaceutical Industry Biotechnology Vaccine Production Sterile Production Facilities API Manufacturing Supply of Purified Media GMP Production Plants Contract Manufacturing (CMO) Advantages Original Bosch Pharmatec Quality Never Put Into Operation High-Quality GMP Version Complete Technical Documentation Available Flexible Retrofitting of Control and Pneumatic Technology According to Customer Requirements Immediately Available Significantly Cheaper Than a Comparable New System The system can be inspected by appointment. We will gladly send you further photos, technical documents and drawings upon request.

Condition: new, Year of construction: 2009, operating hours: 69 h, functionality: fully functional, Mediseal / Körber P-1500 Cartoning Machine for Vials and Eye Drop Bottles – Year of Manufacture: 2009 For sale: a high-quality, intermittently operating, horizontal cartoning machine of the type Mediseal (Klöckner) P-1500, designed for pharmaceutical applications. The machine is suitable for both vials and eye drop bottles as well as comparable primary packaging formats. The system was purchased as new but has never been used in production. Only FAT (Factory Acceptance Test) and SAT (Site Acceptance Test) were performed. With just 69 operating hours, the machine is in virtually as-new condition. Technical Description • Max. output: up to 150 cartons per minute • Operating mode: intermittent, horizontal • Product infeed via magazine, starwheel, and product chain • Automatic erecting of folding cartons using vacuum grippers • Automatic insertion of products and package leaflets • Fully automatic leaflet feeder (RonTech) • Progressive carton closing, outfeed to the right • Option for color code embossing on carton flaps Carton Size Range • Length (C): 65 – 150 mm • Width (A): 35 – 90 mm • Height (B): 15 – 95 mm Formats / Flexibility • Currently equipped with format parts for 5 ml, 10 ml, and 15 ml eye drop bottles • Includes all necessary format and change parts • Highly flexible machine, suitable for additional bottle, vial, and product formats • Fast and reproducible format changes Features • Operation via touchscreen (all controls at eye level) • Operating manual in German and French Machine Data • Manufacturer: Mediseal, Körber (formerly Klöckner), Germany • Model: P-1500 • Machine No.: 43 • Year of manufacture: 2009 • Electrical connection: 220/400 V, 3 Ph, 50 Hz • Required space: approx. 6,250 × 2,800 × 2,200 mm • Weight: approx. 3,500 kg Condition Ijdpfxox Nx Daj Ap Dotn • Unused, virtually as new • Never put into production • Only FAT and SAT performed • Only 69 documented operating hours Original price in 2009 • approx. €700,000 - €750,000 with one format set Videos showing machine in operation available Price On request

Condition: refurbished (used), Year of construction: 2013, functionality: fully functional, PAGO System L600 Pharmaceutical Labeling Machine | Extensively modernized | GMP | Immediately available Manufacturer: PAGO Etikettiersysteme GmbH (Fuji Seal) Model: System L600 Year of manufacture: 2013 For sale is a high-quality PAGO System L600 labeling machine for the pharmaceutical industry. The machine is suitable for labeling vials, injection bottles, and other cylindrical containers in a GMP environment. The machine was already upgraded and modernized at the factory in 2018 to handle additional product formats. In 2022, we purchased the machine used and immediately took it to the manufacturer, Fuji Seal / PAGO Germany. There, it was completely inspected, serviced, and extensively modernized. Investments of €60,200 were made in these measures. Before delivery, a complete Factory Acceptance Test (FAT) was carried out at the Fuji Seal factory. The machine is in very good technical condition and is ready for immediate use. Iedpfx Aszpzbfsp Detn Equipment Laetus/Keyence vision system for print and code inspection New Allen / Novexx thermal transfer printer Siemens PLC control Touchscreen operation Unwinding station Outfeed station Servo drives Stainless steel GMP design Complete protective enclosure Original documentation Technical data Output up to 120 products/min For vials and injection bottles GMP-compliant design Year of manufacture 2013 Manufacturer: PAGO Etikettiersysteme GmbH Why is the machine being sold? For our new pharmaceutical CMO plant, we have purchased two new labeling machines. Due to space limitations, this machine is no longer needed. Advantages Extensive modernization by Fuji Seal / PAGO Documented investment of €60,200 Factory upgrade already in 2018 Complete FAT at the manufacturer Very well-maintained condition Immediately available Significantly cheaper than a new machine A comparable PAGO/Fuji Seal pharmaceutical labeling machine costs over €450,000 in 2026, depending on the equipment and automation. Inspection is possible at any time by appointment. We will gladly send you further photos, videos, and technical documentation upon request.

Condition: used, Year of construction: 2011, functionality: fully functional, machine/vehicle number: L3B031, IMA MISTRAL Y 16 Bottle/Can Air Rinsing Machine – Used, Immediately Available Machine Data: Model: IMA MISTRAL Y 16 Type: Automatic Bottle/Can Air Rinsing and Extraction Machine Serial No.: L3B031 Year of Manufacture: 2011/2012 Manufacturer: IMA S.p.A. / IMA Swiftpack (Italy) Electrical Specifications: 220/380 V, 3 phases, 50 Hz Space Requirements: approx. 400 × 140 × 220 cm Description & Features: This rotary air rinsing machine is designed for pharmaceutical and medical applications, suitable for GMP-compliant internal cleaning of stable, round glass or plastic bottles using sterile compressed air. • Fully automatic bottle cleaning and extraction • Processes up to 200 containers per minute • Includes format parts for plastic bottles Ø 44 mm × height 95 mm • Additional formats included: Ø 40 × 55 mm, Ø 60 × 130 mm • Operation: Bottles are single-lane fed via conveyor and screw separator, transferred into a carousel, gripped by tongs, rotated 180°, and cleaned with nozzles (blowing) and extraction heads (suction). Bottles are then transferred to the conveyor for downstream processing. • Suitable for bottles and cans made of plastic and glass • High level of automation, GMP-compliant design Iedpsw Sfa Ejfx Ap Dstn Documentation & Manuals: • Operating manuals (German, English, Italian) • Electrical circuit diagrams • Layout drawings / guards layout • Spare parts catalog • Blowing diagram / electrical diagram • FAT and SAT documentation • Machine and operator manual in German Scope of Supply: • Complete machine • Spare parts as per catalog • All original documentation (PDFs and printed documents) • Size parts for various bottle sizes Condition: • Used, from pharmaceutical production • Immediately ready for operation after installation • Available immediately Location: Çorlu, Turkey Price: On request

Condition: new, Year of construction: 2020, functionality: fully functional, Equipment: documentation/manual, For sale is a fully procured, modular GMP process system for the production of C1-Esterase Inhibitor (C1-INH) from human plasma. The plant was professionally engineered, procured, and has successfully completed FAT, but has never been installed or put into operation. This is expressly not a used line, but a factory-new project and module package. Year of manufacture: 2020 Condition: brand new, in original packaging Operating hours: 0 Storage: temperature-controlled warehouse SCOPE OF SUPPLY (EXCERPT WITH QUANTITIES) Adsorption / Chromatography (Bay 2 & 3): - 2 adsorption lines (DEAE / QAE) - 2 buffer tanks - 2 pigging systems - 2 cooled transfer lines (pipe-in-pipe) - 4 filter press racks - 4 cooling cascades - 4 CIP loops Precipitation PRE: - 3 pre-precipitation tanks (incl. 1,000 L) - 3 main precipitation tanks - 3 CIP stations - 3 multi-layer filters - 1 vacuum station Buffer Preparation (Bay 2 & 3): - 6 buffer vessels (NaCl, DEAE, QAE buffer) - 6 temperature control skids - 4 media/WFI/CIP distribution units Itodsym Ayfopfx Ap Dsn LEP 2.3 – Washing & Elution Solutions: - 2 washing solution tanks (up to 9,000 L) - 2 elution solution tanks - 4 temperature control units LEP 13 – Ammonium Sulfate System: - 1 preparation tank (3,500 L) - 2 storage/distribution tanks - Solid material crusher - Dosing & neutralization system - Heat-traced pipes Media Distribution: - 1 pharmaceutical NaOH 1M system - 1 technical NaOH 32% system - 1 acetic acid 60% system - Pump and dosing stations Additional Process Tanks: - >15 stainless steel tanks 316L (1,000–9,000 L) - Various skids, distribution and instrumentation units GMP & DOCUMENTATION - URS / requirement specifications per LEP - P&ID diagrams - Layout and sectional drawings - EMSR & instrumentation documentation - FAT documentation - Complete weld certification (digital) - Extensive photo documentation The project documentation is fully available both digitally and additionally physically archived, structured in 316 folders. Process control system connection with pre-configured MES interface is foreseen. Cleanroom integration according to specification. SALE Preferably as a complete system. Modular sale possible if the entire package is not sold. Suitable for plasma fractionators, biopharma manufacturers, CDMOs, or new site establishment projects. Availability: short notice Inspection: by appointment Price: on request

Year of construction: 2017, condition: as good as new (ex-display), functionality: fully functional, Pharmatec Syntegon SVP 250 LF – Formulation System for Sterile and Aseptic Liquid Pharmaceuticals For sale is a Pharmatec Syntegon SVP 250 LF formulation system for Small Volume Parenterals (SVP). The sale is on behalf of Syntegon (manufacturer, formerly Bosch Packaging/Pharmatec GmbH, Dresden). Technical Specifications: - Suitable for aqueous solutions, suspensions, and emulsions - Adaptable processing: terminal sterilization, sterile filtration, aseptic compounding - 2-vessel system for batch sizes of 25–250 L (expandable up to 4 vessels) - Dosing of additives via manway under LAF or pump system - Potent actives (OEB4/OEB5) processing via high-containment valve - CIP/SIP interfaces and pre-configured automation for integration with filling lines - GMP-compliant design, suitable for cleanroom classification Itsdpoxdy Ersfx Ap Den Pricing: - Special price: please submit your offer - Original price in 2018: approx. €1,050,000 - Current list price for similar systems in 2025/2026: €1,415,000 Completion Status & Delivery Time: - Currently, the system is not fully operational, as the automation system including software needs to be reinstalled and certain components require replacement. - Completion will be handled directly by the manufacturer Syntegon, in consultation – expected lead time is approx. 3–4 months. - For comparison: lead time for a new system is approx. 12 months. Special Features: - System was originally built for exhibition purposes (demonstration unit) - Sale is directly on behalf of Syntegon, the original manufacturer - Ideal for pharmaceutical companies seeking a flexible and high-performance SVP system with a manageable delivery time.

Condition: excellent (used), Year of construction: 2020, functionality: fully functional, Manufacturer: Speidel Tank and Vessel Construction Year of manufacture: 2020 Technical specifications: Net capacity: approx. 1,250 liters Material: Stainless steel 1.4404 / AISI 316L Design: insulated (with thermal jacket/insulation jacket) Internal surface: suitable for food/pharmaceutical use Operating pressure: atmospheric (storage tank) Temperature range: suitable for temperature-controlled media Connections: hygienic clamp fittings Manway: available Bottom: conical (complete drainage) Legs: height adjustable Application: The tank is ideally suited for the storage of pharmaceutical, cosmetic, or food-grade liquids. The tank was used as a CIP vessel in a pharmaceutical facility and was operated under hygienic conditions accordingly. Typical applications include: - Intermediate storage of bulk goods - CIP feed tank - Storage of alcohol, cleaning, or disinfectant solutions - Process integration in filling lines Construction: - Premium stainless steel construction (316L) - Insulated tank for temperature-controlled processes - Hygienic design with clamp fittings - Conical bottom for complete residue drainage - Industrial-grade build from German manufacturer Speidel Condition: Iedpey I Skwefx Ap Detn - Very good condition - Used, well maintained - Immediately available FAT / Documentation: - Operation manual available - Manufacturer documentation included Scope of delivery / Documentation: - Complete stainless steel tank - Insulation jacket - Documentation / operation manual - Nameplate present Special features: - German brand quality (Speidel) - Suitable for pharmaceutical, cosmetic, and food applications - Ideal as a CIP feed or buffer tank - Compact design with high quality

Year of construction: 2020, condition: new, functionality: fully functional, Manufacturer BRINOX Machine designation CIP System CS6720 Model LEP12 – CIP module with insulated buffer tank, 200 L Itsdpfx Apoyl H Hte Djn Year of manufacture 2020 Condition New, unused, originally packaged, never installed, never commissioned System type Modular CIP system (Cleaning in Place) on stainless steel frame, fully pre-assembled. Comprising insulated CIP buffer tank, centrifugal pump, heat exchanger, stainless steel piping module, valve technology, measuring and control equipment, as well as media connections. Frame dimensions Approx. 2330 x 1224 x 2127 mm Buffer tank Working volume: 200 liters Total volume: 278 liters Cylindrical design with dished ends according to DIN 28011 Operating pressure: -1 to +3 bar Test pressure: 5.4 bar Permissible temperature: -10 °C to +150 °C Operating temperature: 0 °C to +85 °C Fluid group: 1 Insulation: Glass wool with low chloride content (

Condition: new, Year of construction: 2020, functionality: fully functional, Equipment: documentation/manual, Brinox LEP 11 – Pharmaceutical Chromatography System with CIP Unit New, unused, original packaging Manufacturer: Brinox Model: LEP 11 Version: PP6711 with associated CIP unit CS6711 Condition: New – unused – original packaging (Factory New Condition) Description For sale is a Brinox LEP 11 pharmaceutical chromatography system, consisting of the chromatography panel PP6711 and the associated CIP unit CS6711. The system is completely new, unused, and in its original packaging. It was designed, manufactured, and delivered, but has never been installed or put into operation. This unit is designed for C1-INH chromatography and is used for controlled protein purification using sieve-bottom vessels in a GMP environment. Isdpfx Asyl Ndnep Detn Process Functions • Transfer of loaded QAE resin (slurry) • Washing and elution processes • Transfer of eluate to pre-precipitation vessel • Gel disposal via container station • Fully automatic CIP and SIP cleaning Technical Data • Fully CIP and SIP capable • Design pressure: –0.9 to +6 bar • Design temperature: +2°C to +95°C • Flow rate up to 10 m³/h • Adjustable slurry transfer 0.2 – 3 m³/h Design Features • Product-contact parts made of stainless steel 1.4435 • Electropolished Ra ≤ 0.8 µm • FDA and EU-compliant seals • Drainable construction • Cleanroom panel with tri-clamp connection points • Magnetically monitored transfer arcs • 0.2 µm vent filter CIP Unit CS6711 • Compact stainless steel skid • Centrifugal pump • Shell-and-tube heat exchanger • Adjustable operating pressure • GMP-compliant design The system is in factory-new condition and has never been used in production.

Condition: new, Year of construction: 2020, functionality: fully functional, tank capacity: 3,500 l, Equipment: documentation/manual, BRINOX 3,500 L Storage Tank – 1.4435 – Double Jacket – PED Module G – TÜV SÜD – FAT – 2020 – Like New Manufacturer: BRINOX d.o.o. Type: SVBBHI-3500 Tag No.: BH6772-BH1001 Package 30 Serial Number: 1003462 Year of Manufacture: 2020 Condition: Like new / unused TECHNICAL DATA Product Type: Storage / Process Tank Nominal Volume: 3,500 litres Total Volume: 4,082 litres Jacket Volume: 226 litres Empty Weight: approx. 1,760 kg Product-contacting Material: 1.4435 (AISI 316L pharmaceutical grade) Jacket Material: 1.4404 CE Marking: CE 0036 Permissible Pressure PS (Tank): -1 / +3 bar Permissible Pressure PS (Jacket): -1 / +6 bar Test Pressure PT (Tank): 5.6 bar Test Pressure PT (Jacket): 10.8 bar Permissible Temperature TS: -10 °C to +150 °C Fluid Group: 2 Designed in accordance with AD 2000 regulations Pressure vessel according to PED 2014/68/EU Category IV Module G – Individual Inspection Notified Body: TÜV SÜD Industrie Service GmbH (ID No. 0036) TÜV approval including design review, final inspection and pressure test fully documented. FAT – Factory Acceptance Test The vessel has been fully inspected and released by the manufacturer. Tests carried out include: • Pressure test as per PED • Design review by TÜV SÜD • Visual inspection of all weld seams • Non-destructive testing (RT, PT) • Dimensional and drawing check (as-built) • Review of material certificates • Calibration check of manometers • Verification of markings • Documentation review as per inspection checklist Full FAT and TÜV inspection reports available. EXECUTION • Cylindrical, horizontal storage tank • Double jacket for heating/cooling • High-quality pharmaceutical design • Manhole with round pressure closure • CIP pipework • J-pipe / internal piping • Sight glass DN80 • Multiple spare and process connections • Biocontrol flanges • Heavy-duty mounting blocks / trunnion design • Lifting lugs • Nameplate with complete PED marking DOCUMENTATION – complete and well-structured • EU declaration of conformity • TÜV certificate with inspection report (Module G) • TÜV design assessment and certification Itodpjylnwyefx Ap Den • 3.1 material certificates • Welder lists and work samples • Non-destructive test reports (RT, PT) • Dimensional inspection reports • Manometer calibration reports • Surface and production reports • Parts list • Detailed drawings (body, lid, CIP, J-pipe, etc.) • Operating and maintenance manuals Complete digital documentation folder available. CONDITION • Never put into operation • Was in storage • Interior surface as new • No corrosion • No signs of use • As-new industrial condition • Immediately available SUITABLE FOR • Pharmaceutical solutions • WFI / PW systems • Buffer and media preparation • Chemical media • GMP production facilities • Process and waste management plants SPECIAL FEATURE Premium BRINOX pharmaceutical-grade manufacture with full PED Module G individual inspection by TÜV SÜD, CE 0036 marking and documented FAT testing. Not a standard tank – certified project quality with comprehensive GMP-compliant documentation.

Condition: new, Year of construction: 2020, functionality: fully functional, tank capacity: 3,200 l, Equipment: documentation/manual, BRINOX 3,200 L Solution Tank – 316L – Double Jacket – TÜV / PED Module G – FAT – 2020 – Like New Manufacturer: BRINOX d.o.o. Tag No.: BH6761-BH1001 Serial Number: 1003446 Year of Manufacture: 2020 Condition: Like New / Unused Technical Data Product Type: ELUTION / Solution Tank Volume: 3,200 liters Empty Weight: 1,815 kg Material: 1.4404 (AISI 316L) CE Marking: CE 0036 Tank Pressure Operating Pressure: -1 / +3 bar Test Pressure: 4.6 bar Jacket Pressure (Heating/Cooling Jacket) Operating Pressure: -1 / +6 bar Test Pressure: 10.8 bar Temperature Range: -20°C to +150°C Pressure vessel according to PED 2014/68/EU Module G – Single Inspection Notified Body: TÜV SÜD (Identification No. 0036) Permitted Number of Load Cycles: 7,300 / 5,475 at pressure fluctuation ranges of 3.3 / 4.5 bar TÜV / PED / FAT • EU Certificate of Conformity according to 2014/68/EU • Certificate No.: Z-EU-SI-LJU-20-08-2350154-14124056 • Inspection report available • Pressure test with water successfully completed • Approval by TÜV SÜD Industrie Service GmbH • Factory Acceptance Test (FAT) performed • Module G individual acceptance • Turn-Over Package (TOP) fully available Complete Documentation Available The complete technical documentation package is available, including: • EU Declaration of Conformity and warranty certificates • TÜV certificate with acceptance report • TÜV design review and certification • Nameplate documentation • Assembly drawings • Detailed drawings • Welder lists and weld process qualifications • Work samples • Analysis certificates for welding consumables • Analysis certificates for shielding gases • Manufacturer qualification certificate • Non-destructive testing (NDT) reports • Material certificates (3.1) • Calibration certificates • Internal pressure test report • Dimensional accuracy check • Roughness protocol • Surface treatment report • Operating and maintenance manuals (equipment and components) The documentation scope meets project standards for pharmaceutical plants. Design Features • Double jacket for heating and cooling • Manufactured entirely from stainless steel 316L (1.4404) • High-gloss polished internal surface • Pharmaceutical-grade weld seams • CIP/SIP-capable connections • Multiple manholes / inspection openings • Clamp and flange connections • Instrumentation pre-installed (pressure, temperature, sensors) • Heavy-duty project design • Lifting lugs for crane handling • PED-compliant pressure design Condition • Never used in production • Stock from project surplus • Absolutely clean interior • No corrosion • No signs of use • As-new industrial condition • Immediately available Suitable for • Pharmaceutical solutions • WFI / PW systems • Elution / buffer preparation • Sterile liquid processes • Biotechnology • GMP production plants • CIP media Special Feature This is not a standard tank, but a high-quality BRINOX project-built vessel in genuine pharmaceutical quality featuring: • PED Module G individual inspection • TÜV SÜD approval • FAT performed • Complete welding, material, and inspection documentation Itsdpfsykkbxox Ap Don • Documented surface treatment • 316L construction for sterile applications Project quality for demanding GMP applications – immediately available.

Condition: new, Year of construction: 2020, functionality: fully functional, Equipment: documentation/manual, Package 15 PP6715 – CS6715 Brinox LEP 11 – Pharma Chromatography and CIP System New – original packaging – Factory New Manufacturer: Brinox Model: LEP 11 Version: PP6715 with CIP System CS6715 Condition: New, unused, original packaging Description For sale is a high-quality pharmaceutical chromatography system Brinox LEP 11, consisting of the PP6715 control panel and the corresponding CS6715 CIP unit. The system is completely new, unused, and in the manufacturer's original condition. It was designed for industrial C1-INH chromatography and meets the highest GMP standards. Scope of Functions - Slurry transfer - Washing and elution processes - Transfer to pre-precipitation tanks - Gel disposal - Independent CIP loop Technical Features - Product-contacting components in stainless steel 1.4435 - Electropolished, Ra ≤ 0.8 µm - FDA-compliant sealing systems - CIP/SIP-capable - Operating pressure up to 6 bar - Temperature range up to 95°C - Fully drainable piping CIP Skid CS6715 - Stainless steel frame - Centrifugal pump Isdpfoyl Rqpox Ap Detn - Shell-and-tube heat exchanger - Temperature control of cleaning media - Adjustable feed pressure The system is in factory-new condition with zero operating hours.

Condition: new, Year of construction: 2020, functionality: fully functional, tank capacity: 3,200 l, Equipment: documentation/manual, BRINOX 3,200 L Solution Vessel – 316L – Double Jacket – TÜV / PED Module G – FAT – 2020 – As New Package 17 Manufacturer: BRINOX d.o.o. Tag No.: BH6762-BH1001 Year of manufacture: 2020 Condition: As new / unused TECHNICAL DATA Product type: Elution / Solution Vessel Ijdpfx Apjykkhrj Dotn Volume: 3,200 liters Material: 1.4404 (AISI 316L) CE marking: available (CE 0036) Vessel pressure: Operating pressure: -1 / +3 bar Test pressure: As per TÜV inspection Jacket pressure (heating/cooling jacket): Operating pressure: -1 / +6 bar Test pressure: As per TÜV inspection Temperature range: -20 °C to +150 °C Pressure vessel in accordance with PED 2014/68/EU Module G – Single unit inspection Acceptance by notified body (identification number 0036) FAT – Factory Acceptance Test The vessel was tested as part of a documented FAT. The tests included, among others: • Verification of welding documentation • Visual inspection of weld seams • Leak testing • Pressure testing • Surface roughness inspection • Sensor calibration check • Layout and dimensional inspection • Documentation review The complete FAT report including test protocols is available. SPECIFICATION • Double jacket for heating/cooling • Entirely made of stainless steel 316L • High-gloss polished internal surface • Pharmaceutical-grade weld seams • CIP/SIP-capable connections • Multiple manways / inspection openings • Clamp and flange connections • Instrumentation ready (pressure, temperature, sensors) • Heavy-duty project construction • Lifting lugs for crane handling CONDITION • Never used in production • Surplus stock from project overrun • Interior absolutely clean • No corrosion • No signs of use • As-new industrial condition • Immediately available DOCUMENTATION – complete and structured Comprehensive, project-specific quality and manufacturing documentation is available for the vessel, including: • EU Declaration of Conformity and warranty certificates • TÜV certificate with acceptance report • TÜV design inspection and certification • Material certificates (3.1) • Welder lists and welding procedure qualification records (WPQR/WPS) • Non-destructive testing reports (NDT) • Analysis certificates for welding consumables and shielding gas • Surface roughness protocol • Surface treatment report • Dimensional accuracy check • Internal pressure test • Calibration certificates • Assembly records • Drawings (detail and overall) • Operating and maintenance manuals Complete documentation file available digitally. SUITABLE FOR • Pharmaceutical solutions • WFI / PW systems • Elution / buffer preparation • Sterile liquid processes • Biotechnology • GMP production plants • CIP media SPECIAL FEATURE This is not a standard tank, but a premium BRINOX project build in true pharmaceutical quality with verified pressure design, full PED conformity (Module G), documented FAT testing, and comprehensive quality documentation. Project-level quality for sterile applications – available immediately.

Year of construction: 2020, condition: new, functionality: fully functional, Equipment: documentation/manual, Package 14 PP6713 – CS6713 Brinox LEP 11 – GMP Chromatography System with CIP Skid New – unused – in original packaging Manufacturer: Brinox Model: LEP 11 Version: PP6713 with CIP System CS6713 Condition: New – in original packaging – never installed Description Offered is a pharmaceutical chromatography system LEP 11, consisting of the chromatography panel PP6713 and the corresponding CIP skid CS6713. The system is completely new, unused, and remains in the manufacturer’s original condition. The unit was designed for GMP-grade protein purification as part of C1-INH chromatography. System Features Cleanroom panel for wall integration Transfer lines to sieve-bottom tanks Precipitation vessel connection Gel waste disposal line Complete utility/process piping Technical Specifications Design pressure: –0.9 to +6 bar Design temperature: +2 to +95 °C Electropolished surfaces Ra ≤ 0.8 µm Material: 1.4435 stainless steel Fully drainable GMP-compliant design CIP System CS6713 Stainless steel frame construction Centrifugal pump Shell-and-tube heat exchanger Conductivity, pressure, and temperature monitoring Adjustable CIP supply flow Itjdoyl Rnnepfx Ap Den The system is brand new and has never been in operation.

Condition: used, Year of construction: 2024, functionality: fully functional, 3M Encapsulated System Holder 16EZB – Filter holder for production capsules Manufacturer: 3M Purification Inc. / 3M Separation and Purification Sciences Division Model: 3M™ Encapsulated System Holder 16EZB Year of manufacture: 2024 Location: Marburg, Germany Condition: Used, already in operation New price: approx. 78,000 USD Description: For sale is a high-quality 3M™ Encapsulated System Holder, type 16EZB, for use in biopharmaceutical production, pilot plants, or process development. The filter holder was specifically designed to accommodate 3M production capsules and is suitable for both upstream and downstream processes. The vertical process design ensures optimal media utilization. The system allows for quick capsule changes and reduces cleaning and validation efforts compared to conventional stainless steel filter housings. Technical features: Model: 16EZB Accommodates 1 to 7 multi-cell production capsules Robust stainless steel construction Vertical operating position for optimal media utilization Swivel design for easy loading and unloading Mobile system with industrial swivel casters Locking mechanism with two handles Suitable for pilot and production scale Maximum differential pressure load: 3.4 bar (50 psid) Materials: Frame: Stainless steel 304 End plates: Stainless steel 304 Guide rods: Stainless steel 316 Base: Stainless steel 304 Locking elements: Stainless steel 304 Rollers: Polyurethane on stainless steel construction Application areas: Biopharmaceutical production Cell culture harvest Monoclonal antibodies (mAb) Recombinant proteins Microbial filtration Downstream process steps Pilot and scale-up applications Advantages: No stainless steel filter housings required Reduced cleaning and validation efforts Quick capsule changes Low risk of contamination Space-saving design High process flexibility Isdozbkr Eepfx Ap Dstn Scope of supply: 3M Encapsulated System Holder 16EZB Used, functional Further details and photos on request Inspection: Possible by appointment in Marburg. Price: Negotiable Contact: Further information, technical documents, and inspection appointments on request.

Condition: new, Year of construction: 2020, functionality: fully functional, machine/vehicle number: BH6723-BH1001, tank capacity: 1,000 l, Equipment: documentation/manual, BRINOX 1,000 L Pre-Fill Tank – 1.4435 – Double Jacket – PED Cat. IV Module G – TÜV – FAT – 2020 – As New Manufacturer: BRINOX d.o.o. Type: SVMMBI-1000 Tag No.: BH6723-BH1001 Serial No.: 1003454 Year of Manufacture: 2020 CE Marking: CE 0036 Condition: As new / unused TECHNICAL DATA Product type: Pre-fill / process vessel Nominal volume: 1,000 L Total volume: 1,400 L Net weight: approx. 610–762 kg Product contact material: 1.4435 (AISI 316L) Permissible pressure PS: -1 / +3 bar Test pressure PT: 5.4 bar Permissible temperature TS: -10 / +150 °C Fluid group: 1 Design according to AD 2000 Pressure vessel in accordance with PED 2014/68/EU Category IV Module G – Individual inspection Notified body: TÜV SÜD Identification number: 0036 TÜV CERTIFICATION EU Declaration of Conformity (Module G) Certificate no.: Z-EU-SI-LJU-20-05-2702107-19125214 Inspection report no.: P-EU-SI-LJU-20-05-2702107-19125214 Final inspection in accordance with PED Annex I No. 3.2 carried out Pressure test in accordance with Annex I No. 3.2.2 carried out Acceptance without deviations Permissible load cycle count: 10,000 cycles (1.3 bar) Acceptance date: 20.05.2020 FAT – Factory Acceptance Test Complete works FAT carried out: • Pressure test • Visual inspection of weld seams • NDT testing (RT/PT) • Dimensional inspection • Surface roughness measurement (≤ 0.8 µm) • Calibration test Itedpfx Ajykqmzsp Don • Documentation review FAT fully documented. DESIGN • Cylindrical, horizontal pressure vessel • Double jacket for heating/cooling • Internally electropolished • Pharmaceutical-grade weld finish • Manhole DN 500 • CIP connection • Safety valve • Pressure gauge • Multiple process and measuring nozzles • For pressurised and vacuum operation CONDITION • Never used in production • Factory tested • TÜV Module G certified • As-new industrial condition • No signs of use • Immediately available DOCUMENTATION Complete structured documentation available, including: • EU Declaration of Conformity • TÜV certificate with inspection report • TÜV design assessment • FAT protocols • Material certificates EN 10204 3.1 • WPS/WPQR and welders’ lists • NDT reports • Surface roughness protocols • Internal pressure test • Measurement reports • Calibration certificates • Parts list and drawings • Operating and maintenance manuals Digital documentation folder available. • Pharmaceutical solutions • WFI / PW systems • Buffer and media preparation • Sterile liquid processes • GMP installations • Biotechnology High-quality BRINOX pharmaceutical specification with PED Cat. IV Module G individual inspection by TÜV SÜD (CE 0036) and complete FAT documentation. Not a standard tank – tested project quality. Immediately available.

Condition: used, Year of construction: 2001, functionality: fully functional, Groninger Filling and Capping Line – Type DFK 6001 & KVK 206 Manufacturer: Groninger GmbH, Crailsheim Models: DFK 6001 (volumetric dosing filler) & KVK 206 (dropper inserter/capper) Year of manufacture: 2001 Machine No.: DFK 5265 / KVK 5266 Electrical connection: 220/380 V, 3 phase, 50 Hz Documentation: Machine and operating manual (German) available Line output: According to manufacturer: up to 9,000 units/hour Actual recent operation: approx. 8,000 units/hour Output infinitely variable Technical Data – Filler (DFK 6001): 6-head volumetric dosing filler for free-flowing liquids Currently equipped with stainless steel pumps (dosing range 10–133 ml) General dosing range: 0.15–266 ml Bottles up to Ø 100 mm, max. height 320 mm Ijdpfx Apjw Sd Nrj Dstn Subsurface filling possible (also for foaming products) Pumps can be quickly removed for cleaning and sterilization Filling needles are adjustable in height and laterally Operation via control panel (on right) and dial scale handwheel (at rear) Working area protected by folding glass doors Manual feed via rotary table Ø 1000 mm, onward transport via plastic slat-chain conveyor Technical Data – Capper (KVK 206): Dropper inserter & capping machine Performance range: Object Ø: 20–100 mm Object height: 30–250 mm Cap Ø: 10–60 mm Cap height: 10–60 mm Capacity: max. 9,000 units/hour Closures separated in sorting bowls, fed and placed automatically Press-fit stations and capping heads synchronized Torque clutch adjustable for defined closure force Finished, closed bottles ejected on the right Processed formats: 4 bottle formats: 40 / 50 / 80 / 125 ml Same droppers and screw caps for all formats Dimensions (approx.): Line: 700 × 270 × 225 cm Control cabinet: 180 × 60 × 220 cm Application areas: Pharmaceutical industry Cosmetics industry Chemical industry Special features: Compact, GMP-compliant stainless steel line Flexible dosing ranges, also suitable for foaming liquids Ready for immediate use Condition: Well-maintained used condition Available immediately from Çorlu, Turkey Price: On request

Condition: new, Year of construction: 2020, functionality: fully functional, Equipment: documentation/manual, Machine Description BRINOX LEP 12 – CIP System Precipitation PRE LEP 12 CS6725 Package 5 Manufacturer BRINOX Prozess- und Edelstahltechnik GmbH, Offenburg Year of Manufacture 2020 Serial Number 1003614 Technical Data Compact CIP skid system in stainless steel frame design. Product designation: LEP 12 – CIP System Precipitation PRE. Dimensions approx. 1520 x 970 x 1994 mm. Product-contact parts: Stainless steel 1.4435. Frame and structural components: Stainless steel 1.4301. Integrated shell-and-tube heat exchanger by NEUMO. Centrifugal pump in hygienic design. Piping fully welded in pharmaceutical grade. Insulated media lines. Fittings incl. GEMÜ ball valves. Various integrated pressure gauges and measuring instruments. Calibrated pressure measurement system (Fluke pressure transducer, measuring range −1 to 20 bar, resolution 0.001 bar, accuracy 0.06 % FS). Media Connections: NaOH Acetic acid CIP supply CIP return Black steam Black steam condensate Neutralized wastewater Pressure tightness test performed with compressed air. Test pressure range approx. 3.19–3.24 bar. Maximum measured pressure drop < 0.015 bar during the test period. Result: passed. Iodpfsyl H Taex Ap Djtn Application CIP cleaning system for pharmaceutical process plants, especially for precipitation vessels. Suitable for caustic and acid cleaning as well as steam integration. Designed for hygienic applications in pharmaceutical production. Construction Welded, compact skid design with robust stainless-steel frame construction. Hygienic piping layout with defined media paths. Integrated shell-and-tube heat exchanger for CIP media temperature control. Integrated process pump, valve technology, and instrumentation on a compact frame. General tolerances according to EN ISO 13920. Industrial design with crane lugs for transport. Condition New, unused, and in original packaging. The system was only inspected as part of the FAT process and has never been in production use. FAT / Documentation Status Complete Factory Acceptance Tests carried out. Pressure tightness tests successfully passed. Calibration certificates available. All test protocols fully documented. Complete Documentation List FAT documentation Pressure test protocols Calibration certificates P&ID 3D drawings Material and welding documentation Nameplate and manufacturer documentation Special Features Pharma-grade material selection. Compact, immediately ready-to-use skid unit. High-quality components from renowned manufacturers. Complete technical documentation available. Immediately available.

Condition: new, Year of construction: 2020, functionality: fully functional, Equipment: documentation/manual, Manufacturer: BRINOX Product: LEP13.1 – AS-Batch Temperature Control Unit System type: Temperature control unit for ammonium sulfate batch system Year of manufacture: 2020 Serial number: 1003620 Tag number: MR-ASF-ASF61-KK6770 Equipment number: 20022748 Iodjyl Izxspfx Ap Djtn Media Connections / Process Data WCOV – Chilled water supply: 6 °C WCOR – Chilled water return: 12 °C WSV – Process/municipal water AIP10 – Control compressed air 6 bar Design as a closed temperature control module with integrated pump and heat exchanger technology. Dimensions Overall dimensions as per layout: approx. 1920 x 1435 x 1573 mm (L x W x H) Compact, skid-mounted unit with welded stainless steel frame. Construction Frame construction in stainless steel Fully insulated piping (industrial insulation) Stainless steel shell-and-tube heat exchanger Electrical inline water heater WT1011 Pump PU1021 Pump PU9203 Heat exchanger WT1001 Expansion vessel BH9701 Fittings: GEMÜ shut-off valves Pneumatically actuated valves Manual ball valves Pressure gauges Sensors and instrumentation as per P&ID Complete piping and component labeling provided. Condition New and in original packaging. Not yet put into operation in production. Factory new condition. Supplied directly by the manufacturer Brinox. FAT / Test Status FAT carried out. Leak test: Test medium: Compressed air Test pressure: approx. 3 bar Holding time: 1 hour Result: Passed Calibration: Pressure gauge calibrated Measuring range: 0–10 bar Calibration certificate available Traceable to national standards Documentation Turn-Over-Package complete Included documents: FAT plan FAT report Non-conformance form Layout drawing check Maintenance and calibration accessibility check P&ID review Leak test report Calibration certificates Documentation check Factory certificate 2.1 according to EN 10204 LBM material list incl. EU declarations List of installed components – equipment List of installed components – instrumentation points (PLT) Material parts list for as-built isometry Key Features GMP-compliant construction Pharma/biotech project quality Full traceability Compact plug-and-play skid design Completely piped, insulated, and ready to connect Immediately available

Condition: new, Year of construction: 2020, functionality: fully functional, Equipment: documentation/manual, BRINOX LEP13.2 – AS Storage Tempering Unit – GMP – Year of Manufacture 2020 – Like New Manufacturer: BRINOX Process Systems LEP13.2 KK6772 Package 12 System type: LEP13.2 – AS Storage Tempering Unit Project: Ammonium sulphate system Year of manufacture: 2020 Serial number: 1003624 Tag number: MR-ASF-ASF61-KK6772 Location: Germany DESCRIPTION For sale is a nearly new LEP13.2 tempering unit in pharmaceutical GMP-compliant design, manufactured by BRINOX Process Systems. The unit is constructed as a compact, pre-assembled skid unit and was designed for use in an ammonium sulphate storage system. Complete project and FAT documentation is available. TECHNICAL DATA Type: LEP13.2 – AS Storage Tempering Unit Medium: Ammonium sulphate Design: Pharma / GMP Materials: Stainless steel 1.4435 / 1.4301 Control air pressure: 6 bar Pressure and leak testing performed FAT successfully completed MAIN COMPONENTS 2x KSB Movitec centrifugal pumps Alfa Laval plate heat exchanger Electric instantaneous water heater Reflex expansion vessel Samson control valve GEMÜ ball valves (manual & pneumatic) Labom pressure gauges Comprehensive sensors & measuring instruments Insulated pipework Stainless steel skid frame construction APPLICATIONS Temperature control of process media Use in GMP-regulated production areas Pharmaceutical and biotechnology plants Media circuits with temperature control CONSTRUCTION Compact, closed skid unit Fully piped Professionally insulated piping High-quality industrial components Service-friendly layout Completely dismountable and transportable CONDITION Condition: New, original packaging Year of manufacture: 2020 Project-specific unit Hardly any operating hours Visually and technically in excellent condition DOCUMENTATION FAT documentation Pressure test certificates P&ID diagrams Layout drawings Factory certificates according to EN10204 Iodpfeyl Na Nsx Ap Djtn Materials lists EU declarations of conformity FEATURES Complete GMP documentation High-quality brand components Ideal for pharmaceutical and biotech applications Immediately available Significantly below new price

Condition: new, Year of construction: 2020, functionality: fully functional, Equipment: documentation/manual, Manufacturer: BRINOX Itedpsyl It Iefx Ap Don Type: LEP2.3 – Wash Solution Temperature Control Unit Year of Manufacture: 2020 Serial Number: 1003507 LEP2.3 KK6761 Package 8 Tag No.: MR-INH-VPR61-KK6761 Equipment No.: 20023781 Technical Data System Type: Temperature control unit / heating and cooling module for wash solution (CIP or process washing system) Design: Compact, fully pre-assembled skid unit in robust stainless steel frame construction, crane-liftable via integrated lifting points. Frame and Construction: Welded stainless steel construction in industrial design, free-standing, multi-level piping configuration for optimal space utilization. Maintenance-friendly access from multiple sides. Integrated cable trays. Piping: Stainless steel process piping in hygienic design, welded and partially flanged. Multilayer thermal insulation of main lines and apparatus. Integrated drain and vent fittings. Valve Technology: Multiple manual ball valves (GEMÜ) in main and bypass circuits. Pneumatically actuated control and shut-off valves for automatic temperature regulation. Diaphragm and control valves integrated in the heating and cooling circuit. Instrumentation and Control: Temperature measurement points in both supply and return lines. Pressure sensors in the process section. Integrated flow measurement. Electrical junction box with protective labeling. Automatic temperature control via pneumatic control valve. Heat Exchanger: Cylindrical stainless steel heat exchanger, insulated and integrated into the piping system. Designed for controlled heating and/or cooling of the wash solution in a closed loop. Pump Technology: Two electrically driven centrifugal pumps with red-painted motors for process recirculation within the temperature control unit. Electrical: Electrical junction box with warning markings. Wired sensors and actuators. Prepared for integration into a central PLC or process control system. Application This system is used for precise temperature regulation of a wash solution within a pharmaceutical or biotechnological process system. Typical areas of application include CIP systems, production plant washing stations, and temperature-controlled cleaning processes in the pharmaceutical and biotechnology sectors. The wash solution circulates in a closed loop via pumps, is temperature controlled by the integrated heat exchanger, and continuously monitored by sensors. Temperature is regulated automatically via pneumatic control valves to maintain defined setpoints accurately. Construction Compact modular skid design with fully insulated main lines. Stainless steel surfaces in hygienic industrial finish. Clearly organized media routing and structured piping layout. Crane-transportable via integrated lifting points. Condition Year of manufacture 2020. Very good visual and technical condition. Professional execution in pharmaceutical plant engineering. FAT / Documentation Typically supplied with CE conformity, Factory Acceptance Test (FAT), and technical documentation including P&ID diagrams and material certificates for product-contacting components. Special Features Fully insulated temperature control module in a compact, high power density design. High-quality valve technology (GEMÜ). Multiple integrated measurement and control points. Suitable for validated pharmaceutical processes. Industrial, pre-assembled skid solution with clearly structured media routing.

Condition: new, Year of construction: 2020, functionality: fully functional, Equipment: documentation/manual, Manufacturer: BRINOX Type: LEP 11 – CIP Skid Year of Manufacture: 2020 Design: Pharma / GMP Condition: New, unused, original packaging LEP 11 CS6710 Package 1 Machine Type Pharmaceutical CIP (Cleaning-in-Place) system as a compact package unit mounted on a stainless steel frame. Application Automated cleaning of process plants, chromatography systems, vessels and piping in the pharmaceutical, biotech and chemical industries. Suitable for NaOH, acetic acid, WFI, PW, and other cleaning agents. Technical Data Heating capacity of the CIP medium: from +5 °C to +80 °C in max. 10 minutes Pump performance: 1 – 4 m³/h (adjustable) Operating pressure at CIP supply: 1 – 3 bar (adjustable) Measurement ranges: Flow: 0 – 10 m³/h Temperature: 0 – +150 °C Pressure: 0 – 6 bar Design pressure: -0.9 to +6 bar Design temperature: +2 to +95 °C Construction • Compact package unit on stainless steel frame • CIP supply pump as centrifugal pump • Shell-and-tube heat exchanger with leak-proof design • Height-adjustable ball feet • Fully drainable construction • Maintenance-friendly design • Industrial heavy-duty build Material & GMP Design • Product- and cleaning-agent-contacted components made of stainless steel 1.4435 • Electropolished surfaces Ra ≤ 0.8 μm • FDA-compliant seals (EPDM / PTFE / silicone) • Designed for NaOH 0.3 mol/L at +80 °C • Resistant to acetic acid, WFIH, WFIC, PUW Documentation & Quality • Complete GMP documentation • CE conformity • 3.1 material certificates • Complete welding protocols • Weld seam documentation incl. photo documentation • Documented pressure and tightness tests • FAT documents available • Drainability and final rinse certificates available Condition • New • Unused • Original packaging Iodpfxoyl Hwlo Ap Dotn • No production hours • Immediately available Key Features • Very high thermal cleaning performance • Fully adjustable process operation • Top pharmaceutical GMP design • High-quality European components • Investment-safe system including complete documentation Location: Germany Viewing by appointment possible

Condition: new, Year of construction: 2020, functionality: fully functional, Equipment: documentation/manual, Manufacturer BRINOX d.o.o. Project Number B-0001113-LEP2.3 LEP 2.3 KK6762 Package 9 Module M024 Product Description LEP2.3 – Wash Solution Temperature Control Unit Serial Number 1003572 Equipment Number 20022782 Tag Number MR-INH-VPR61-KK6762 Year of Manufacture 2020 Technical Data System Type Pharma temperature control skid for precise temperature regulation of wash and elution solutions. Constructed as a compact, multi-level stainless steel frame design with fully integrated pump, heat exchanger, and valve technology. Dimensions Length 1920 mm Width 1365 mm Height 1840 mm Design Fully pre-assembled, insulated temperature control skid Pharmaceutical design according to GMP requirements Industrial stainless steel frame construction Materials Product-contact parts: Stainless steel 1.4435 / 1.4571 Frame construction: Stainless steel 1.4301 Welds as per EN ISO 13920 D Insulation Completely insulated piping and equipment Itjdpeyl Iwtofx Ap Dsn Closed-cell high-performance insulation with black protective sheathing Main Components PU1021 Process Pump PU9203 Chilled Medium Pump WT1001 Plate Heat Exchanger WT1011 Finned Tube Heat Exchanger BH9701 Expansion Tank Pneumatic Control Valves GEMÜ Stainless Steel Ball Valves Pressure Transmitters Temperature Measurement Points Pressure Gauges Electrical Junction Box with Warning Labels Stainless Steel Cable Trays Media Chilled Brine Supply / Return Wash Solution Process Medium Control Air 6 bar All media connections sealed at factory and packaged securely for transport. Leak Testing Performed as pressure test with compressed air. DP-01 Medium: Compressed Air Test Pressure: 3.15 bar Pressure Drop: 0.13 bar Date: 27.07.2020 Result: Passed DP-02 Medium: Compressed Air Test Pressure: 3.28 bar Pressure Drop: 0.07 bar Date: 26.07.2020 Result: Passed Pressure holding time: 1 hour each No leaks detected Calibration Certificates Calibration Laboratory: LOTRIČ Metrology Certificates according to EN ISO/IEC 17025 Measurement Ranges: –1 to 20 bar and 0 to 10 bar Calibration performed Documentation Scope FAT Plan and Report Deviation Report Layout Drawing Check Maintenance Inspection P&ID Leak Test Report Calibration Certificates Works Certificate 2.1 EN10204 Material List As-Built Isometrics Complete Turn-Over Package Inspection Status FAT performed Pressure test passed Calibrations available PED-compliant design Pharma documentation complete Application Temperature control of wash and elution solutions in biopharmaceutical production facilities Suitable for GMP environments Condition New system Original packaging Unused Year of manufacture: 2020 Factory condition Fully documented Immediately available

Condition: new, Year of construction: 2020, functionality: fully functional, tank capacity: 1,000 l, Equipment: documentation/manual, BRINOX 1,000 L Pre-Fill Vessel – 1.4435 – Double Jacket – PED Cat. IV Module G – TÜV – FAT – 2020 – As New Manufacturer: BRINOX d.o.o. Itsdpfeykt T Rox Ap Don Type: SVMMBI-1000 Tag No.: BH6725-BH1001 Serial No.: 1003455 Year of manufacture: 2020 CE Marking: CE 0036 Condition: As new / unused TECHNICAL SPECIFICATIONS Product type: Pre-fill / process vessel Nominal volume: 1,000 L Total volume: 1,400 L Empty weight: 762 kg Product contact material: 1.4435 Permissible pressure (PS): -1 / +3 bar Test pressure (PT): 5.4 bar Permissible temperature (TS): -10 / +150 °C Fluid group: 1 Design according to AD 2000 Pressure vessel compliant with PED 2014/68/EU Category IV Module G – Single Unit Inspection Notified body: TÜV SÜD Notification number: 0036 FAT – Factory Acceptance Test Full factory FAT conducted and documented. Testing includes pressure test, NDT (non-destructive testing), dimensional inspection, surface roughness inspection, and documentation release. FEATURES • Cylindrical horizontal pressure vessel • Double jacket for heating/cooling • Interior electropolished • Pharmaceutical-grade welding • Manway DN500 • Multiple process and instrument connections • Safety valve • CIP connections • Suitable for pressure and vacuum operation CONDITION • Never used in production • TÜV Module G certified • As-new industrial condition • Immediately available DOCUMENTATION – complete and available Comprehensive structured documentation including: • EU Declaration of Conformity • TÜV certificate with inspection report • TÜV design assessment • FAT documentation • Material certificates • Welding lists and WPS/WPQR • NDT reports • Surface roughness protocol • Surface treatment report • Internal pressure test • Dimensional protocol • Calibration certificate (pressure gauge) • Component drawings • Assembly parts list • Operation and maintenance manuals (equipment & components) • Qualification certificates • Analysis certificates for welding consumables and shielding gases Complete digital documentation file available. APPLICATIONS • Pharmaceutical industry • WFI / PW • GMP-compliant plants • Sterile liquid processes • Biotechnology High-quality BRINOX pharmaceutical version with PED Cat. IV Module G single unit inspection by TÜV SÜD, complete FAT, and full technical documentation. Immediately available.